hmgcoareductaseinhibitors

A substance that blocks an enzyme needed by the body to make cholesterol and lowers the amount of cholesterol in the blood. HMG-CoA reductase inhibitor ...

HMG CoA reductase inhibitors inhibit mesangial cell proliferation and production of macrophage chemotactic factors, thereby slowing down renal disease ...

These Statins inhibit the action of enzyme HMG-CoA reductase (3-hydroxy-3-methylglutaryl coenzyme A reductase) that catalyzes the rate-limiting step in ...

2021年4月28日 — β-Hydroxy β-methylglutaryl-CoA (HMG-CoA) reductase inhibitors, more popularly known as statins, work by reducing the cholesterol levels in ...

2023年4月17日 — Statins (also called HMG-CoA reductase inhibitors) block an enzyme called HMG-CoA reductase (3-hydroxy-3-methylglutaryl coenzyme A ...

由 JA Tobert 著作 · 2003 · 被引用 1086 次 — Inhibition of HMG-CoA reductase reduces levels of mevalonate, which leads to a reduction in the regulatory sterol pool, which in turn causes ...

Statins act by competitively inhibiting HMG-CoA reductase, the rate-limiting enzyme of the mevalonate pathway. Because statins are similar in structure to HMG- ...

由 A Markowska 著作 · 2020 · 被引用 16 次 — Statins, also known as HMG-CoA inhibitors, are a class of bioactive small molecules that efficiently reduce the levels of cholesterol, ...

由 唐正乾 著作 — Rosuvastatin: a new HMG-CoA reductase inhibitors for hypercholesterolemia. Formulary 2002; 37: 179-85. 22.Igel M, Sudhop T, Bergmann KV. Pharmacology of 3- ...